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Designed to provide an introduction to the major classes of therapeutic agents. The major classes of receptors and their ligands (agonists and antagonists) that result in pharmacological effects and drug action. Investigation, under the direction of one or more faculty members, of a problem of limited scope. Students may register in more than one section per term.

The Company expects that the additional patients in the fifth cohort will complete cycle 1 dosing early in the second quarter of 2017.Nanomaterials, with their size range (1-100 nm) that corresponds to basic biological materials such as DNA, vastly increased surface area (1000 m/g) and unique mechanical, electronic, photonic and magnetic properties are projected to have a wide range of applications from drug and gene delivery to biomedical imaging.The major advantage of using nanomaterials as a carrier for anticancer drugs is the possibility of targeted delivery to the tumor, their ability to enclose or bind thousands of molecules of a drug and deliver to the required site and to overcome solubility and stability issues.[1-4] In addition, nanoplatforms like liposomes, lipid nanoparticles, dendrimers, micelles, gold nanoparticles can offer solutions to various problems in diagnosis and treatment of cancer.*Corresponding author: Gopalakrishna Pillai, Ph D, Professor, Sullivan University College of Pharmacy, 2100 Gardiner Lane, Louisville KY 40205, USA, Tel.: 1 5; Fax.: 1 5, E-mail: /g) and unique mechanical, electronic, photonic and magnetic properties are projected to have a wide range of applications from drug and gene delivery to biomedical imaging and more recently to personalized medicine.The major advantages of using nanomaterials as a carrier for anticancer agents are the possibility of targeted delivery to the tumor, tumor imaging, their ability to hold thousands of molecules of a drug and also their ability to overcome solubility, stability and resistance issues.In addition to this passive targeting based mainly on size, the nanoparticle surface may be modified with a variety of ligands that would interact with specific receptors over-expressed on the surface of the tumor cells, thus imparting specificity for active targeting.